Published January 1, 2012 | Version v1
Journal article Open

Functional deficits and morphological changes in the neurogenic bladder match the severity of spinal cord compression

  • 1. Akdeniz Univ, Dept Physiol, Fac Med, TR-07058 Antalya, Turkey
  • 2. Akdeniz Univ, Dept Anat, Fac Med, TR-07058 Antalya, Turkey
  • 3. Univ Cologne, Dept Orthoped & Trauma Surg, D-50931 Cologne, Germany
  • 4. Univ Cologne, Childrens Hosp, D-50931 Cologne, Germany
  • 5. Univ Cologne, Inst Anat 1, D-50924 Cologne, Germany
  • 6. Univ Cologne, Jean Uhrmacher Inst Clin ENT Res, D-50924 Cologne, Germany
  • 7. Univ Thessaloniki, Dept Histol & Embryol, GR-54006 Thessaloniki, Greece
  • 8. Univ Tubingen, BG Trauma Ctr, Burn Unit, Dept Hand Plast & Reconstruct Surg, Tubingen, Germany
  • 9. Univ Jena, Dept Otorhinolaryngol, Jena, Germany

Description

Following spinal cord injury (SCI), loss of spinal and supraspinal control results in desynchronisation of detrusor vesicae (parasympathicus) and external urethral sphincter (sympathicus) activity. Despite recovery of lower urinary tract function being a high priority in patients with SCI, effective treatment options are unavailable largely because mechanisms are poorly understood.

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