Published January 1, 2015 | Version v1
Journal article Open

Microbiologic, Pharmacokinetic, and Clinical Effects of Corneal Collagen Cross-Linking on Experimentally Induced Pseudomonas Keratitis in Rabbits

  • 1. Acibadem Univ, Dept Ophthalmol, Istanbul, Turkey
  • 2. Istanbul Univ, Expt Med Res Inst, Biol Lab Anim & Biomed Applicat Tech, Istanbul, Turkey
  • 3. Namik Kemal Univ, Dept Ophthalmol, Tekirdag, Turkey
  • 4. Acibadem Univ, Dept Microbiol, Istanbul, Turkey
  • 5. Acibadem Univ, Dept Biochem, Istanbul, Turkey
  • 6. Acibadem Maslak Hosp, Dept Pathol, Istanbul, Turkey

Description

Purpose: To determine the effects of corneal collagen cross-linking (CXL) on the penetration of topical 0.5% moxifloxacin, on the number of colony-forming units (CFUs) in the cornea, and on the clinical course in a rabbit eye model of experimentally induced Pseudomonas aeruginosa keratitis.

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