Published January 1, 2015
| Version v1
Journal article
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Comparison of Mesenchymal Stem Cells Isolated From Pulp and Periodontal Ligament
Creators
- 1. Selcuk Univ, Fac Dent, Res Ctr, TR-42079 Konya, Turkey
- 2. Selcuk Univ, Mol Genet & Biotechnol Labs, Dept Soil Sci & Plant Nutr, TR-42079 Konya, Turkey
- 3. Karabuk Univ, Fac Med, Dept Biostat, Karabuk, Turkey
- 4. Kocaeli Univ, Ctr Stem Cell & Gene Therapies Res & Practice, Inst Hlth Sci, Stem Cell Dept, Kocaeli, Turkey
- 5. Liv Hosp, Ctr Regenerat Med & Stem Cell Res & Mfg, Istanbul, Turkey
Description
Background: Cell-based therapy using mesenchymal stem cells (MSCs) seems promising to obtain regeneration of dental tissues. A comparison of tissue sources, including periodontal ligament (PDL) versus pulp (P), could provide critical information to select an appropriate MSC population for designing predictable regenerative therapies. The purpose of this study is to compare the proliferation and stemness and the MSC-specific and mineralized tissue-specific gene expression of P-MSCs and PDL-MSCs.
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