Published January 1, 2015
| Version v1
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Serum lipids and cardiac function correlate with nitrotyrosine and MMP activity in coronary artery disease patients
Creators
- 1. Univ Szeged, Dept Biochem, Cardiovasc Res Grp, H-6720 Szeged, Hungary
- 2. Semmelweis Univ, MTA SE Cardiovasc Imaging Res Grp, Heart & Vasc Ctr, H-1122 Budapest, Hungary
- 3. Univ Szeged, Dept Biochem, Metab Dis & Cell Signaling Res Grp, Budapest, Hungary
Description
AimsPeroxynitrite-matrix metalloproteinase (MMP) signalling has been shown to contribute to myocardial ischaemia/reperfusion injury and heart failure and to be influenced by hyperlipidaemia in preclinical models. Therefore, here we investigated the correlation between the markers of peroxynitrite-MMP signalling and hyperlipidaemia in patients with significant coronary stenosis.
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