Yayınlanmış 1 Ocak 2015 | Sürüm v1
Dergi makalesi Açık

Serum lipids and cardiac function correlate with nitrotyrosine and MMP activity in coronary artery disease patients

  • 1. Univ Szeged, Dept Biochem, Cardiovasc Res Grp, H-6720 Szeged, Hungary
  • 2. Semmelweis Univ, MTA SE Cardiovasc Imaging Res Grp, Heart & Vasc Ctr, H-1122 Budapest, Hungary
  • 3. Univ Szeged, Dept Biochem, Metab Dis & Cell Signaling Res Grp, Budapest, Hungary

Açıklama

AimsPeroxynitrite-matrix metalloproteinase (MMP) signalling has been shown to contribute to myocardial ischaemia/reperfusion injury and heart failure and to be influenced by hyperlipidaemia in preclinical models. Therefore, here we investigated the correlation between the markers of peroxynitrite-MMP signalling and hyperlipidaemia in patients with significant coronary stenosis.

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