Amplification yield enhancement of short DNA templates using bulk and surface-attached amine-functionalized single-wall carbon nanotubes

In this report, water dispersions of pristine, amine-functionalized, and carboxyl-functionalized single-wall carbon nanotubes were introduced into model DNA amplification reactions in order to exploit the effects of surface charge, dispersion quality, and concentration of the carbon nanomaterials in the final amplification yield. The magnetic beads that were covalently modified with the functionalized carbon nanotubes were also evaluated under equal conditions to observe the difference between bulk and surface-attached nanotubes.