Yayınlanmış 1 Ocak 2015 | Sürüm v1
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Chlorogenic Acid Containing Bioinspired Polyurethanes: Biodegradable Medical Adhesive Materials

  • 1. Inonu Univ, Dept Chem, TR-44280 Malatya, Turkey
  • 2. Hacettepe Univ, Dept Chem, TR-06532 Ankara, Turkey

Açıklama

Highly adhesive bioinspired polyurethanes (PUs) based on the chlorogenic acid (CLA) were prepared from 4,4'-methylenebis (cyclohexyl isocyanate) (MCI) and polyethylene glycol 200 (PEG 200). The polyurethanes exhibited the lowest glass transition temperature (T-g), improved thermal stability and good adhesive properties. The highest adhesion strength was found as 373.3 +/- 47.5 kPa for 10% CLA containing PUs. The polyurethanes were observed to be biodegradable and were in the range of 19-24% for 8 weeks as depending on chlorogenic acid containing of PUs. As a result, prepared biocompatible-adhesive bioinspired polyurethanes are good candidates for medical applications as a tissue adhesive material.

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