Published January 1, 2020 | Version v1
Journal article Open

Effect of kirenol on the interaction between the WNT/beta-Catenin and RUNX2/TCF/LEF1 pathways in fracture healing in vivo

  • 1. Erciyes Univ, Sch Med, Dept Orthoped & Traumatol, Kayseri, Turkey
  • 2. Kayseri City Hosp, Clin Orthoped & Traumatol, Kayseri, Turkey
  • 3. Erciyes Univ, Sch Pharm, Dept Pharmacol, Kayseri, Turkey
  • 4. Erciyes Univ, Sch Med, Dept Radiol, Kayseri, Turkey
  • 5. Erciyes Univ, Sch Med, Dept Histol, Kayseri, Turkey

Description

Objective: This study aimed to determine the effects of a natural diterpenoid, kirenol, on fracture healing in vivo in an experimental rat model of femur fracture and investigate its potential mechanism of action via the Wnt/beta-catenin pathway.

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