Published January 1, 2015 | Version v1
Journal article Open

The synthesis of an octasubstituted monohydroxylated phthalocyanine designed to investigate the effect of the presence of active moieties

  • 1. Gebze Tech Univ, Dept Phys, TR-41400 Gebze, Kocaeli, Turkey
  • 2. Gebze Tech Univ, Dept Chem, TR-41400 Gebze, Kocaeli, Turkey

Description

A monohydroxylated octasubstituted phthalocyanine, aimed at being used as a synthon for further conjugation, has been designed to offer rigorous comparison conditions to study the effect of the presence of an active moiety, compared to its non-functionalized symmetric analogs. After the validation of the concept using computational methods, the designed phthalocyanine was prepared and exhibited the expected suitable electronic absorption properties. Biotin conjugation was performed.

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