Yayınlanmış 1 Ocak 2015 | Sürüm v1
Dergi makalesi Açık

Antioxidant activities of several Scutellaria taxa and bioactive phytoconstituents from Scutellaria hastifolia L.

  • 1. Yeditepe Univ, Fac Pharm, Dept Pharmacognosy, TR-34755 Istanbul, Turkey
  • 2. Univ Athens, Sch Pharm, Dept Pharmacognosy & Chem Nat Prod, GR-15771 Athens, Greece
  • 3. Aristotle Univ Thessaloniki, Sch Pharm, Lab Pharmacognosy, Thessaloniki 54124, Greece
  • 4. Aristotle Univ Thessaloniki, Sch Pharm, Dept Pharmaceut Chem, Thessaloniki 54124, Greece

Açıklama

This study was designed to evaluate the phenolic profiles and antioxidant potentials of different solvent extracts of four Scutellaria L. (Lamiaceae) taxa, S. hastifolia, S. velenovskyi, S. albida ssp. albida and S. orientalis ssp. pinnatifida, which are used in,traditional medicines for various purposes. Among the investigated species, S. hastifolia was selected for further biological and phytochemical studies according to the results of preliminary screening assays. Phytochemical studies on S. hastifolia yielded a new phenylethanoid glycoside (hastifolioside) together with 16 known metabolites. The structures of the compounds were established on the basis of spectroscopic analyses. The antioxidant potentials and the antiinflammatory activities of the crude extracts of S. hastifolia as well as the isolates were evaluated through DPPH radical scavenging capability, linoleic acid lipid peroxidation inhibition and soybean LOX inhibition assays. (C) 2015 Elsevier B.V. All rights reserved.

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