Published January 1, 2015
| Version v1
Journal article
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Protective Effects of Molsidomine Against Cisplatin-Induced Nephrotoxicity
Creators
- 1. Inonu Univ, Fac Med, TR-44280 Malatya, Turkey
- 2. Inonu Univ, Dept Urol, Fac Med, TR-44280 Malatya, Turkey
- 3. Inonu Univ, Dept Physiol, Fac Med, TR-44280 Malatya, Turkey
- 4. Inonu Univ, Dept Pharmacol, Fac Med, TR-44280 Malatya, Turkey
- 5. Inonu Univ, Dept Pathol, Fac Med, TR-44280 Malatya, Turkey
Description
Background. Cisplatin, an effective chemotherapeutic agent, is used for the treatment of several types of cancers. However, cisplatin has some severe side effects such as nephrotoxicity. On the other hand, molsidomine, a NO donor, has anti-oxidative and vasodilator effects.
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