Published January 1, 2015 | Version v1
Journal article Open

Resveratrol improves hepatic insulin signaling and reduces the inflammatory response in streptozotocin-induced diabetes

  • 1. Karamanoglu Mehmetbey Univ, Dept Biol, KO Sci Fac, TR-70100 Karaman, Turkey
  • 2. Afyon Kocatepe Univ, Dept Med Pharmacol, Fac Med, Afyon, Turkey
  • 3. Afyon Kocatepe Univ, Dept Med Biochem, Fac Med, Afyon, Turkey
  • 4. Afyon Kocatepe Univ, Dept Histol Embryol, Fac Med, Afyon, Turkey
  • 5. Afyon Kocatepe Univ, Ataturk Vocat Sch Hlth Serv, Dept Lab Med, Afyon, Turkey

Description

Diabetes mellitus is a heterogeneous metabolic disorder essentially characterized by deficiency of insulin secretion, insulin receptor or post-receptor events. This study aims to investigate the effects of resveratrol administration on the metabolic characteristics, hepatic functions, histopathological features and insulin signaling pathway components in streptozotocin induced diabetes.

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