Published January 1, 2015
| Version v1
Journal article
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EVALUATION OF THE CHITOSAN-COATING EFFECTIVENESS ON A DENTAL TITANIUM ALLOY IN TERMS OF MICROBIAL AND FIBROBLASTIC ATTACHMENT AND THE EFFECT OF AGING
Creators
- 1. Balgat Oral & Dent Hlth Ctr, TR-06520 Ankara, Turkey
- 2. Middle E Tech Univ, Dept Biomed Engn, TR-06800 Ankara, Turkey
- 3. Yuzuncu Yil Univ, Dept Mech Engn, TR-65080 Van, Turkey
- 4. Middle E Tech Univ, Dept Engn Sci, TR-06800 Ankara, Turkey
- 5. Gazi Univ, Dept Microbiol, Fac Dent, TR-06500 Ankara, Turkey
- 6. Ankara Univ, Dept Prosthodont, Fac Dent, TR-06500 Ankara, Turkey
Description
The aim of this study was to obtain a biocompatible and antimicrobial implant surface by coating Ti6Al4V with chitosan which can be used to create a smooth transmucosal region for a faster and better wound healing and an increased bioactivity. Ti6Al4V plates were first abraded and ultrasonically cleaned and then coated with chitosan. In order to simulate the conditions of an oral environment, a group of coated plates were treated in a thermocycle apparatus. The coatings were evaluated with SEM, EDS, XRD and FTIR spectroscopy. The fibroblastic cell behavior was determined using HGF-1 cells. P. gingivalis was used to assess the effectiveness of chitosan as an antimicrobial coating.
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