Published January 1, 2015
| Version v1
Journal article
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Does tamoxifen citrate prevent pulmonary fibrosis due to silica inhalation?
Creators
- 1. Iskenderun State Hosp, Izmir, Turkey
- 2. Izmir Univ, Fac Med, Izmir, Turkey
- 3. Kafkas Univ, Fac Med, Kars, Turkey
- 4. Ankara Occupat Dis Hosp, Ankara, Turkey
- 5. Iskenderun State Hosp, Anesthesiol & Reanimat, Mardin, Turkey
- 6. Kecioren Educ & Res Hosp, Dept Pathol, Ankara, Turkey
- 7. Ankara Occupat Dis Hosp, Dept Pulmonol, Ankara, Turkey
- 8. Hacettepe Univ, Fac Med, Dept Med Biochem, TR-06100 Ankara, Turkey
- 9. Ankara Numune Training & Res Hosp, Ankara, Turkey
- 10. Ankara Educ & Res Hosp, Ankara, Turkey
Description
BACKGROUND: As shown in several studies, besides being used in breast cancer, tamoxifen is also known for its antifibrotic effects via reducing the serum TGF-beta levels. We investigated the possible preventive effect of tamoxifen in rats exposed to silica particles depending on the antifibrotic effect.
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