Yayınlanmış 1 Ocak 2015
| Sürüm v1
Dergi makalesi
Açık
Synthesis of new 4-aza-indoles via acyl azides
- 1. Erciyes Univ, Fac Pharm, Dept Pharmacol, TR-38039 Kayseri, Turkey
- 2. Middle E Tech Univ, Dept Chem, TR-06800 Ankara, Turkey
Açıklama
We hereby report the preparation of new azaindole derivatives starting from 2-(2-ethoxy-2-oxoethyl) nicotinic acid. Conversion of a half ester into acyl azide followed by Curtius rearrangement gave the corresponding isocyanate. Trapping of the isocyanate with different nucleophiles produced urea and urethane derivatives. Intramolecular cyclization reactions gave the target compounds. (C) 2014 Elsevier Ltd. All rights reserved.
Dosyalar
bib-42c93845-1f6c-4a8d-a2c7-551242f1ff3f.txt
Dosyalar
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