Published January 1, 2015
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Paclitaxel-loaded niosomes for intravenous administration: pharmacokinetics and tissue distribution in rats
- 1. Ankara Univ, Fac Pharm, Dept Pharmaceut Technol, TR-06100 Ankara, Turkey
- 2. Ankara Univ, Fac Pharm, Dept Pharmacol, TR-06100 Ankara, Turkey
Description
Background/aim: The purpose of this study was to investigate and compare the pharmacokinetic behavior and tissue distribution of paclitaxel, delivered as commercial preparation Taxol or through Span 40 niosomes, after intravenous injection to rats.
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