Yayınlanmış 1 Ocak 2015
| Sürüm v1
Dergi makalesi
Açık
PAT1 inversely regulates the surface Amyloid Precursor Protein level in mouse primary neurons
Oluşturanlar
- 1. Univ Paris 05, Sorbonne Paris Cite, INSERM, Fac Med,UMR 894, Paris, France
- 2. Univ Naples 2, Sch Med, Dept Biochem Biophys & Gen Pathol, Naples, Italy
Açıklama
Background: The amyloid precursor protein (APP) is a key molecule in Alzheimer disease. Its localization at the cell surface can trigger downstream signaling and APP cleavages. APP trafficking to the cell surface in neurons is not clearly understood and may be related to the interactions with its partners. In this respect, by having homologies with kinesin light chain domains and because of its capacity to bind APP, PAT1 represents a good candidate.
Dosyalar
bib-2c3816b7-312f-469b-8269-54b703946918.txt
Dosyalar
(230 Bytes)
| Ad | Boyut | Hepisini indir |
|---|---|---|
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md5:821604fe9fe087ccd11c1d3c3553fc01
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230 Bytes | Ön İzleme İndir |