Published January 1, 2019
| Version v1
Journal article
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Quercetin inhibits swarming motility and activates biofilm production of Proteus mirabilis possibly by interacting with central regulators, metabolic status or active pump proteins
- 1. Cukurova Univ, Fac Pharm, Dept Pharmaceut Microbiol, TR-01380 Adana, Turkey
- 2. Izmir Katip Celebi Univ, Fac Pharm, Dept Pharmaceut Microbiol, TR-35040 Izmir, Turkey
- 3. Ege Univ, Fac Med, Dept Med Microbiol, TR-35040 Izmir, Turkey
- 4. Ege Univ, Fac Pharm, Dept Pharmaceut Microbiol, TR-35040 Izmir, Turkey
Description
Background: Via its virulence factors such as swarm differentiation, biofilm and hemolysin production, urease enzyme, Proteus mirabilis causes urinary tract infections (UTIs), especially in complicated cases. Anti-pathogenic compounds attenuate the virulence of bacteria without showing 'cidal' activity and carry the potential to be used in the prevention and treatment of infectious diseases.
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