Published January 1, 2019
| Version v1
Journal article
Open
Discovery of therapeutic agents for prostate cancer using genome-scale metabolic modeling and drug repositioning
Creators
- 1. KTH Royal Inst Technol, Sci Life Lab, SE-17121 Stockholm, Sweden
- 2. Marmara Univ, Dept Bioengn, Istanbul, Turkey
Description
Background: Genome-scale metabolic models (GEMs) offer insights into cancer metabolism and have been used to identify potential biomarkers and drug targets. Drug repositioning is a time-and cost-effective method of drug discovery that can be applied together with GEMs for effective cancer treatment.
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