Published January 1, 2019
| Version v1
Journal article
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The prognostic significance of glutamic acid decarboxylase antibodies in patients with chronic pancreatitis undergoing total pancreatectomy with islet autotransplantation
Creators
- 1. Univ Minnesota, Schulze Diabet Inst, Minneapolis, MN USA
- 2. Univ Minnesota, Dept Surg, Box 242 UMHC, Minneapolis, MN 55455 USA
- 3. Univ Minnesota, Dept Lab Med & Pathol, Minneapolis, MN 55455 USA
Description
Aim. - Islet autotransplantation (IAT) is considered a 'non-immune' model of islet transplant, with no risk for autoimmune-mediated beta cell loss, but we have previously observed de novo type 1 diabetes in one total pancreatectomy with islet autotransplantation (TPIAT) recipient. We aimed to investigate the clinical significance of glutamic acid decarboxylase antibodies (GADA), as a sensitive marker for autoimmune diabetes mellitus (DM), in patients with chronic pancreatitis undergoing TPIAT.
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