Published January 1, 2019
| Version v1
Journal article
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Effect of surgically guided axonal regrowth into a 3-way-conduit (isogeneic trifurcated aorta) on functional recovery after facial-nerve reconstruction: Experimental study in rats
Creators
- 1. Univ Witten Herdecke, CMMC, Dept Neurosurg, Cologne, Germany
- 2. Univ Cologne, Sch Dent & Oral Med, Dept Prosthet Dent, Cologne, Germany
- 3. Aristotle Univ Thessaloniki, Dept Histol & Embryol, Thessaloniki, Greece
- 4. Univ Cologne, Dept Anat 1, Joseph Stelzmann Str 20, D-50931 Cologne, Germany
- 5. Akdeniz Univ, Fac Med, Dept Anat, Antalya, Turkey
Description
Background: The "post-paralytic syndrome" after facial nerve reconstruction has been attributed to (i) malfunctioning axonal guidance at the fascicular (branches) level, (ii) collateral branching of the transected axons at the lesion site, and (iii) intensive intramuscular terminal sprouting of regenerating axons which causes poly-innervation of the neuromuscular junctions (NMJ).
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