Published January 1, 2019 | Version v1
Journal article Open

Antidepressant-Like Effects of Ceftriaxone in Chronic Unpredictable Mild Stress Model in Rats: The Importance of Reuptake Time of Glutamate

  • 1. Kafkas Univ, Fac Med, Dept Pharmacol, Kars, Turkey
  • 2. Marmara Univ, Fac Pharm, Dept Pharmacol & Psychopharmacol Res Unit, Istanbul, Turkey
  • 3. Ataturk Univ, Fac Med, Dept Psychiat, Erzurum, Turkey
  • 4. Ataturk Univ, Fac Med, Dept Pharmacol, Erzurum, Turkey

Description

Objective: We aimed to indicate the relationship between depression and glutamate, and to reveal the effect of escitalopram, an antidepressant, which is widely used in depression treatment and reuptake parameters of glutamate, and to treat depression with ceftriaxone, one of the beta lactam antibiotics which increased the number and activity of glutamate transporters.

Files

bib-47f5de8e-02d7-4824-a849-55611f26e01a.txt

Files (278 Bytes)

Name Size Download all
md5:938926b67c6d7a0bac36da8c8cce7eb1
278 Bytes Preview Download