Published January 1, 2019
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An In Vitro Study on the Cytotoxicity and Genotoxicity of Silver Sulfide Quantum Dots Coated with Meso-2,3-dimercaptosuccinic Acid
- 1. Hitit Univ, Sungurlu Vocat High Sch, Hlth Programs, Corum, Turkey
- 2. Hacettepe Univ, Fac Pharm, Dept Pharmaceut Toxicol, Ankara, Turkey
- 3. Koc Univ, Grad Sch Mat Sci & Engn, Istanbul, Turkey
- 4. Koc Univ, Coll Sci, Dept Chem, Istanbul, Turkey
Description
Objectives: Silver sulfide (Ag2S) quantum dots (QDs) are highly promising nanomaterials in bioimaging systems due to their high activities for both imaging and drug/gene delivery. There is insufficient research on the toxicity of Ag2S QDs coated with meso-2,3-dimercaptosuccinic acid (DMSA). In this study, we aimed to determine the cytotoxicity of Ag2S QDs coated with DMSA in Chinese hamster lung fibroblast (V79) cells over a wide range of concentrations (5-2000 mu g/mL).
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