Published January 1, 2019 | Version v1
Journal article Open

Development of a water-soluble 3-formylBODIPY dye for fluorogenic sensing and cell imaging of sulfur dioxide derivatives

  • 1. Bingol Univ, Dept Food Engn, TR-12000 Bingol, Turkey
  • 2. Bilkent Univ, UNAM Natl Nanotechnol Res Ctr, TR-06800 Ankara, Turkey
  • 3. Izmir Inst Technol, Fac Sci, Dept Chem, TR-35430 Izmir, Turkey

Description

A new water-soluble, highly fluorogenic 3-formylBODIPY dye that enables the sensing of SO2 derivatives in aqueous buffers and cancer cells is reported. The quaternary ammonium group appended through the mesa-position of the BODIPY dye ensures water solubility. The probe exhibits high specificity for cytosolic (bi)sulfites and fluoresces brightly in human lung adenocarcinoma cells (A549). (C) 2019 Elsevier Ltd. All rights reserved.

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