Published January 1, 2019 | Version v1
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The interaction between P2X7Rs and T-type calcium ion channels in penicillin-induced epileptiform activity

  • 1. Univ Ondokuz Mayis, Med Sch, Dept Physiol, TR-55139 Samsun, Turkey
  • 2. Univ Ondokuz Mayis, Med Sch, Dept Biochem, Samsun, Turkey

Description

Limited information exists on the link between purinergic class P2X7 receptors (P2X7Rs) and calcium ion channels in epilepsy; no data has been reported regarding the interaction between P2X7Rs and T-type calcium ion channels in epilepsy. Thus, this study is an evaluation of the role that T-type calcium ion channels play in the effect of P2X7Rs on penicillin-induced epileptiform activity.

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