Published January 1, 2019 | Version v1
Journal article Open

Clinical significance of progastrin-releasing peptide, neuron-specific enolase, chromogranin a, and squamous cell cancer antigen in pulmonary neuroendocrine tumors

  • 1. Erciyes Univ, Fac Med, Dept Pulm Med, Kayseri, Turkey
  • 2. Hlth Sci Univ, Fac Med, Dept Pulm Med, Kayseri, Turkey
  • 3. Erciyes Univ, Fac Med, Dept Biochem, Kayseri, Turkey
  • 4. Erciyes Univ, Fac Med, Dept Thorac Surg, Kayseri, Turkey
  • 5. Erciyes Univ, Fac Med, Dept Pathol, Kayseri, Turkey
  • 6. Turkish Hlth Inst, Ankara, Turkey

Description

Background/aim: It is not always easy to diagnose pulmonary neuroendocrine tumors (PNETs). The aim of the present study is to make a differential diagnosis by studying the same markers in patients with non-small-cell lung carcinoma (NSCLC), patients with benign lung disease (chronic obstructive pulmonary disease and pneumonia), and healthy volunteers to determine the roles of these markers in pulmonary neuroendocrine tumor diagnosis and to identify their power.

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