Yayınlanmış 1 Ocak 2019
| Sürüm v1
Dergi makalesi
Açık
Investigation of tyrosinase inhibition by some 1,2,4 triazole derivative compounds: in vitro and in silico mechanisms
Oluşturanlar
- 1. Karadeniz Tech Univ, Fac Sci, Dept Chem, TR-61080 Trabzon, Turkey
- 2. Karadeniz Tech Univ, Fac Pharm, Dept Analyt Chem, Trabzon, Turkey
- 3. Karadeniz Tech Univ, Macka Vocat High Sch, Trabzon, Turkey
Açıklama
Background: Tyrosinase plays a central role in the biosynthesis pathway of melanin pigment. Melanin protects human skin against radiation and its unusual levels cause some skin disorders such as pregnancy scar, oldness spots and melanoma. Tyrosinase has also been linked to Parkinson's and other neurodegenerative diseases. In addition, melanin plays a critical role as a defense molecule for insects during wound healing and is important for their life. Therefore, determination of inhibitor molecules for tyrosinase has a promising potential for therapies of some diseases and is an alternative method for keeping insects under control.
Dosyalar
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Dosyalar
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