Published January 1, 2019 | Version v1
Journal article Open

Inflammation-mediated fetal injury by maternal granulocyte-colony stimulating factor and high-dose intra-amniotic endotoxin in the caprine model

  • 1. Suleyman Demirel Univ, Fac Med, Dept Obstet & Gynecol, Isparta, Turkey
  • 2. Mehmet Akif Ersoy Univ, Fac Vet Med, Dept Obstet & Gynecol, Burdur, Turkey
  • 3. Mehmet Akif Ersoy Univ, Fac Vet Med, Dept Pathol, Burdur, Turkey
  • 4. Cukurova Univ, Fac Ceyhan Vet Med, Dept Pathol, Adana, Turkey
  • 5. Isparta Univ Appl Sci, Fac Agr Sci & Technol, Dept Anim Sci, Isparta, Turkey
  • 6. Kutahya Hlth Sci Univ, Fac Med, Dept Histol & Embryol, Kutahya, Turkey

Description

Objective: To define a novel experimental model with maternal intravenous (i.v.) granulocyte-colony stimulating factor (G-CSF) followed by a single- and high-dose of 20 mg intra-amniotic (IA) endotoxin to induce fetal brain injury in the preterm fetal goat.

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