Published January 1, 2019 | Version v1
Journal article Open

c-Myc Inhibitor 10074-G5 Induces Murine and Human Hematopoietic Stem and Progenitor Cell Expansion and HDR Modulator Rad51 Expression

  • 1. Istanbul Tech Univ KOSGEB, Onkim Stem Cell Technol, Istanbul, Turkey
  • 2. Univ Minnesota, Fac Med, Minneapolis, MN USA
  • 3. Anadolu Med Ctr, Bone Marrow Transplantat Ctr, Kocaeli, Turkey
  • 4. Yeditepe Univ, Fac Engn, Dept Genet & Bioengn, Regenerat Biol Res Lab, Istanbul, Turkey

Description

Background: c-Myc plays a major role in the maintenance of glycolytic metabolism and hematopoietic stem cell (HSC) quiescence.

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