Published January 1, 2019 | Version v1
Journal article Open

; The Role of the Local Bone Marrow Renin-Angiotensin System in Multiple Myeloma

  • 1. Istanbul Univ, Istanbul Fac Med, Dept Internal Med, Istanbul, Turkey
  • 2. Istanbul Univ, Aziz Sancar Inst Expt Res, Dept Genet, Istanbul, Turkey
  • 3. Istanbul Univ, Istanbul Fac Med, Dept Pathol, Istanbul, Turkey
  • 4. Istanbul Univ, Istanbul Fac Med, Dept Biochem, Istanbul, Turkey

Description

Objective: Angiotensin II promotes growth and angiogenesis via type 1 receptors (AGTR1) in certain tumors. In this study, we examine the bone marrow AGTR1 expression in multiple myeloma (MM) and its relationship with the regulation of angiogenesis and prognostic factors.

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