Published January 1, 2020 | Version v1
Journal article Open

Impact of pH on the activity of co-used antimicrobials against resistant Escherichia coli strains of animal origin

  • 1. Bursa Uludag Univ, Fac Vet Med, Dept Pharmacol & Toxicol, Lab Mol Pharmacol, Bursa, Turkey
  • 2. Bursa Uludag Univ, Inst Hlth Sci, Bursa, Turkey

Description

In this study, combination antimicrobial therapy, due to its higher potential against resistant bacteria, was evaluated for the inhibition of multidrug-resistant E. coli strains. The influence of pH as an environmental variable on the activity of antimicrobial combinations was evaluated by calculating the factional concentration indexes at pH values 5.0, 6.0, 7.3, and 8.0.

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