Assessment of LXR alpha agonist activity and selective antiproliferative efficacy: a study on different parts of Digitalis species

Objective: Aerial parts and roots of three Digitalis species (Digitalis davisiana Heywood, Digitalis viridiflora Lindley and Digitalis grandiflora Miller; Plantaginaceae) were investigated from the viewpoint of cytotoxicity to identify the biologically active parts. Playing a role in cell proliferation and tumor growth, LXR alpha agonist activity also has become of interest to researchers investigating its relationship with the cytotoxicity.