Published January 1, 2019
| Version v1
Journal article
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Assessment of LXR alpha agonist activity and selective antiproliferative efficacy: a study on different parts of Digitalis species
- 1. Hacettepe Univ, Dept Pharmacognosy, Fac Pharm, Ankara, Turkey
- 2. Aichi Gakuin Univ, Dept Lab Med Resources, Sch Pharm, Grad Sch Pharm, Nagoya, Aichi, Japan
Description
Objective: Aerial parts and roots of three Digitalis species (Digitalis davisiana Heywood, Digitalis viridiflora Lindley and Digitalis grandiflora Miller; Plantaginaceae) were investigated from the viewpoint of cytotoxicity to identify the biologically active parts. Playing a role in cell proliferation and tumor growth, LXR alpha agonist activity also has become of interest to researchers investigating its relationship with the cytotoxicity.
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