Published January 1, 2014
| Version v1
Journal article
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The Effects of high fat diets with and without N-Acetylcysteine supplementation on the lipin-1 levels of serum and various tissues in rats
Creators
- 1. Karadeniz Tech Univ, Fac Med, Dept Med Biochem, Trabzon, Turkey
- 2. Karadeniz Tech Univ, Fac Med, Dept Physiol, Trabzon, Turkey
Description
Objective: Obesity is a public health problem, but the struggle against obesity continues to increase every day. Lipin-1 is an adipokine that modulates lipid metabolism and glucose homeostasis. The aims of the current study were to compare the levels of lipin-1 in serum and tissues (liver, lung, heart, pancreas and kidney) in rat fed with low fat diet (LFD), high fat diet (HFD) and N-acetylcysteine (NAC) supplemented HFD, and to determine the relationships of the lipin-1 levels in serum and tissues with the levels of serum glucose and lipid parameters.
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