Published January 1, 2014 | Version v1
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Synthesis and in vitro study of new highly boronated phthalocyanine

  • 1. Russian Acad Sci, AN Nesmeyanov Inst Organoelement Cpds, Moscow 119991, Russia
  • 2. Tech Univ Istanbul, Dept Chem, TR-34469 Istanbul, Turkey
  • 3. DI Mendeleev Russian Chem Technol Univ, Moscow 125047, Russia
  • 4. Beijing Univ Chem Technol, Coll Mat Sci & Engn, Beijing 100029, Peoples R China

Description

A new highly boronated Zn(II)-phthalocyanine with eight cobalt bis(dicarbollide) units (144 boron atoms) was prepared and its intracellular accumulation and distribution in GL6 human glioblastoma cells were studied. It was found that the boronated phthalocyanine undergoes strong aggregation in intracellular environment.

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