Published January 1, 2014
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Annexin V Expression and Anti-Annexin V Antibodies in Type 1 Diabetes
- 1. Ankara Univ, Sch Pharm, Dept Biochem, TR-06100 Ankara, Turkey
- 2. Ankara Univ, Sch Med, Dept Endocrinol & Metab, TR-06100 Ankara, Turkey
Description
Background: Annexin V (AnxV) has potent anticoagulant properties and regulatory functions for apoptosis and inflammation. Antibodies against annexin V (anti-AnxVs) may inhibit AnxV functions, leading to thrombosis during autoimmune diseases. Type 1 diabetes is an autoimmune disease and related with an ongoing autoimmune inflammation and thrombotic complications. There is no study evaluating anti-AnxVs/AnxV in a disease setting.
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