Yayınlanmış 1 Ocak 2014 | Sürüm v1
Dergi makalesi Açık

Synthesis of tertiary propargylic phosphonates by addition of trialkynylaluminum reagents to acyl phosphonates and investigation of their antimicrobial activities

  • 1. Middle E Tech Univ, Dept Chem, TR-06531 Ankara, Turkey
  • 2. Canakkale Onsekiz Mart Univ, Fac Engn & Architecture, Dept Chem Engn, Canakkale, Turkey
  • 3. Eskisehir Osmangazi Univ, Grad Sch Nat & Appl Sci, Eskisehir, Turkey
  • 4. Eskisehir Osmangazi Univ, Fac Sci & Arts, Dept Biol, Eskisehir, Turkey

Açıklama

A series of propargylic alcohols containing phosphonates was synthesized by addition reactions of tris-(propynyl) and tris-(phenylethynyl) aluminum reagents to acyl phosphonates in good yields. Aromatic moieties of the acyl phosphonates with electron-withdrawing groups generally resulted in better isolated chemical yield. Selected propargylic phosphonates were tested for antimicrobial activities. Compounds 3a and 3h showed noticeable antifungal activity, especially against molds.

Dosyalar

10-3906-kim-1402-6.pdf

Dosyalar (155.7 kB)

Ad Boyut Hepisini indir
md5:3bed92ffbcf4552dfe11fc65b8934357
155.7 kB Ön İzleme İndir