Published January 1, 2014 | Version v1
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Synthesis, X-ray Analysis, and Biological Activities of Novel Oxazolidinethiones

  • 1. Hacettepe Univ, Dept Basic Pharmaceut Sci, Fac Pharm, TR-06100 Ankara, Turkey
  • 2. Hacettepe Univ, Dept Pharmaceut Microbiol, Fac Pharm, TR-06100 Ankara, Turkey
  • 3. Hacettepe Univ, Dept Engn Phys, TR-06800 Ankara, Turkey

Description

Oxazolidinethione compounds were synthesized starting from racemic and enantiopure -amino alcohols. The molecular structure of oxazolidinethione 6a was elucidated by single-crystal x-ray crystallography. Oxazolidinethione compounds screened for antimicrobial activity showed mild minimum inhibitory concentration values.

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