Yayınlanmış 1 Ocak 2014
| Sürüm v1
Dergi makalesi
Açık
Activation of Histone Deacetylase-6 Induces Contractile Dysfunction Through Derailment of alpha-Tubulin Proteostasis in Experimental and Human Atrial Fibrillation
Açıklama
Background Atrial fibrillation (AF) is characterized by structural remodeling, contractile dysfunction, and AF progression. Histone deacetylases (HDACs) influence acetylation of both histones and cytosolic proteins, thereby mediating epigenetic regulation and influencing cell proteostasis. Because the exact function of HDACs in AF is unknown, we investigated their role in experimental and clinical AF models.
Dosyalar
bib-36691d57-ff26-4269-ba15-50584c37f651.txt
Dosyalar
(362 Bytes)
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362 Bytes | Ön İzleme İndir |