Published January 1, 2014 | Version v1
Journal article Open

Different Types of Cell Cycle- and Apoptosis-Related Gene Expressions Alter in Corticosteroid-, Vincristine-, and Melphalan-Resistant U-266 Multiple Myeloma Cell Lines

  • 1. Middle E Tech Univ, Mol Biol & Biotechnol R&D Ctr, Cent Lab, TR-06531 Ankara, Turkey
  • 2. Bayindir Hosp, Clin Hematol, Ankara, Turkey
  • 3. Middle E Tech Univ, Dept Biol Sci, TR-06531 Ankara, Turkey

Description

Objective: Deregulation of the cell cycle and apoptosis mechanisms in normal cells causes many problems, including cancer. In this study, a genome-wide expression analysis of cell cycle- and apoptosis-related genes in corticosteroid-, vincristine-, and melphalan-resistant U-266 multiple myeloma cell lines was conducted.

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