Yayınlanmış 1 Ocak 2014 | Sürüm v1
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SYNTHESIS OF NEW TANDOSPIRONE ANALOGUES CARRYING 1-(3-(TRIFLUOROMETHYL)PHENYL)PIPERAZINE

  • 1. Yildiz Tekn Univ, Fac Sci & Arts, Istanbul, Turkey

Açıklama

New tandospirone analogues containing a 1-[3-(trifluoromethyl) phenyl] piperazine (TFMPP) moiety have been synthesized by hydroarylation reactions with Pd(OAc)(2). The perhydroisoindole derivatives were obtained by the reaction of reduced starting material with aryl-(heteroaryl) iodides under the same conditions. Spiro-1,3-indandionolylpyrrolidine derivatives having an array of stereocenters are reported.

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