Yayınlanmış 1 Ocak 2020 | Sürüm v1
Dergi makalesi Açık

Design of ocular drug delivery platforms and in vitro - in vivo evaluation of riboflavin to the cornea by non-interventional (epi-on) technique for keratoconus treatment

  • 1. Hacettepe Univ, Fac Pharm, Dept Pharmaceut Technol, TR-06100 Ankara, Turkey
  • 2. Inonu Univ, Fac Pharm, Dept Pharmaceut Technol, TR-44280 Malatya, Turkey
  • 3. Hitit Univ, Fac Med, Dept Ophthalmol, TR-19030 Corum, Turkey

Açıklama

Aim: Keratoconus is a common and progressive eye disease characterized by thinning and tapering of the cornea. This degenerative eye disease is currently treated in the clinic with an interventional technique ("epi-off") that can cause serious side effects as a result of the surgical procedure. The aim of this project is to design innovative formulations for the development of a riboflavin-containing medicinal product to develop a non-invasive ("epi-on") keratoconus treatment as an alternative to current treatment modalities.

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