Published January 1, 2020
| Version v1
Journal article
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Design of ocular drug delivery platforms and in vitro - in vivo evaluation of riboflavin to the cornea by non-interventional (epi-on) technique for keratoconus treatment
Creators
- 1. Hacettepe Univ, Fac Pharm, Dept Pharmaceut Technol, TR-06100 Ankara, Turkey
- 2. Inonu Univ, Fac Pharm, Dept Pharmaceut Technol, TR-44280 Malatya, Turkey
- 3. Hitit Univ, Fac Med, Dept Ophthalmol, TR-19030 Corum, Turkey
Description
Aim: Keratoconus is a common and progressive eye disease characterized by thinning and tapering of the cornea. This degenerative eye disease is currently treated in the clinic with an interventional technique ("epi-off") that can cause serious side effects as a result of the surgical procedure. The aim of this project is to design innovative formulations for the development of a riboflavin-containing medicinal product to develop a non-invasive ("epi-on") keratoconus treatment as an alternative to current treatment modalities.
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