Published January 1, 2016 | Version v1
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A quantitative adaptation of the Wayne test for pyrazinamide resistance

  • 1. Asociac Benef PRISMA, San Miguel, Peru
  • 2. Univ Peruana Cayetano Heredia, Lima, Peru
  • 3. Univ Peruana Cayetano Heredia, Fac Sci, Res & Dev Labs, Lab TB Infect Dis, Lima, Peru

Description

Background: Pyrazinamide (PZA) is the most important drug against the latent stage of tuberculosis (TB) and is used in both first and second line treatment regimens. The continued increase in multi-drug resistant TB and the prevalence of PZA resistance makes the development of alternative assays for prompt identification of PZA resistance all the more important.

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