Published January 1, 2016 | Version v1
Journal article Open

Synthesis of novel chiral bisoxazoline ligands with a norbornadiene backbone: use in the copper-catalyzed enantioselective Henry reaction

  • 1. Ahi Evran Univ, Fac Arts & Sci, Dept Chem, Kirsehir, Turkey
  • 2. Middle E Tech Univ, Dept Chem, Fac Arts & Sci, TR-06531 Ankara, Turkey

Description

Novel chiral bisoxazoline ligands based on norbornadiene were synthesized and used for the asymmetric Henry reaction. Various aromatic aldehydes were converted into chiral beta-nitro alcohols with high yields and moderate to acceptable enantioselectivities under the optimized reaction conditions.

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