Published January 1, 2016 | Version v1
Journal article Open

Granulosa cell and oocyte mitochondrial abnormalities in a mouse model of fragile X primary ovarian insufficiency

  • 1. Izmir Katip Celebi Univ, Sch Med, Dept Histol & Embryol, Izmir, Turkey
  • 2. Inonu Univ, Sch Med, Dept Histol & Embryol, Malatya, Turkey
  • 3. Univ Vita Salute San Raffaele, IRCCS San Raffaele Hosp, Dept Obstet & Gynecol, IVF Unit, Milan, Italy
  • 4. Univ Vita Salute San Raffaele, IRCCS San Raffaele Hosp, Lab Clin Mol Biol & Cytogenet, Milan, Italy
  • 5. Univ Calif Davis, MIND Inst, Dept Mol Biosci, Davis, CA 95616 USA
  • 6. Morgan State Univ, Dept Biol, Baltimore, MD 21239 USA
  • 7. NIDDK, Cellular & Mol Biol Lab, NIH, Bethesda, MD 20892 USA

Description

STUDY HYPOTHESIS: We hypothesized that the mitochondria of granulosa cells (GC) and/or oocytes might be abnormal in a mouse model of fragile X premutation (FXPM).

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