Published January 1, 2020
| Version v1
Journal article
Open
Personalized Tumor Growth Prediction Using Multiscale Modeling
Creators
- 1. Karadeniz Tech Univ, Biostat & Med Informat, Trabzon, Turkey
- 2. Middle East Tech Univ, Canc Syst Biol Lab, Ankara, Turkey
- 3. Izmir Democracy Univ, Mech Engn, Izmir, Turkey
- 4. Karadeniz Tech Univ, Trabzon, Turkey
- 5. Karadeniz Tech Univ, Physiol, Trabzon, Turkey
- 6. Karadeniz Tech Univ, Med Oncol, Trabzon, Turkey
Description
Purpose: Cancer is one of the most complex phenomena in biology and medicine. Extensive attempts have been made to work around this complexity. In this study, we try to take a selective approach; not modeling each particular facet in detail but rather only the pertinent and essential parts of the tumor system are simulated and followed by optimization, revealing specific traits. This leads us to a pellucid personalized model which is noteworthy as it closely approximates existing experimental results.
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