Published January 1, 2016
| Version v1
Journal article
Open
Asymmetric transfer hydrogenation of ketones by N,N-containing quinazoline-based ruthenium(II) complexes
Creators
- 1. Kilis 7 Aralik Univ, Fac Sci & Letters, Dept Chem, TR-79100 Kilis, Turkey
- 2. Kahramanmaras Sutcu Imam Univ, Fac Sci & Letters, Dept Chem, TR-46100 Kahramanmaras, Turkey
- 3. Osmaniye Korkut Ata Univ, Fac Sci & Letters, Dept Chem, TR-80000 Osmaniye, Turkey
- 4. Dicle Univ, Fac Sci & Letters, Dept Chem, TR-21280 Diyarbakir, Turkey
Description
The novel set of quinazoline-based chiral ligands was synthesized starting from optically pure amino acids. Coordination with RuCl2(PPh3)dppb gave ruthenium(II) N-heterocyclic complexes 4b-d. The structure of complex 4b was fully illuminated by X-ray crystallography. The steric environment of these chiral ruthenium complexes 4b-d was evaluated in asymmetric transfer hydrogenation (ATH) of prochiral ketones in the presence of (NaOPr)-Pr-i by using 2-propanol as the hydrogen source and solvent. The resultant catalytic system can achieve very good enantioselectivities (up to 91%) and high yields (up to 99%). (C) 2015 Elsevier B.V. All rights reserved.
Files
bib-6205855a-bb5d-4099-8b89-b2dbca445288.txt
Files
(263 Bytes)
| Name | Size | Download all |
|---|---|---|
|
md5:25fe15ee102d06efdf9870ba8efff22d
|
263 Bytes | Preview Download |