Published January 1, 2016
| Version v1
Journal article
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Efficacy of N-acetylcysteine in preventing amphotericin B induced acute kidney injury
Creators
- 1. Marmara Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey
- 2. Marmara Univ, Sch Med, Subdept Hematol, Dept Internal Med, Istanbul, Turkey
- 3. Koc Univ, Sch Med, Subdept Hematol, Dept Internal Med, Istanbul, Turkey
Description
Objectives: Previously, in an animal study we showed that N-acetylcysteine (NAC) could decrease deoxycholate amphotericin B (DAmB) induced renal tubular apoptosis. In this clinical study, we aimed to evaluate the efficacy of NAC in preventing acute kidney injury (AKI) in febrile neutropenic patients with invasive pulmonary aspergillosis treated with DAmB.
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