Published January 1, 2016
| Version v1
Journal article
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Effect of permeability enhancers on paracellular permeability of acyclovir
- 1. Inonu Univ, Dept Pharmaceut Technol, Fac Pharm, Malatya, Turkey
- 2. Hacettepe Univ, Dept Pharmaceut Technol, Fac Pharm, TR-06100 Ankara, Turkey
Description
Objectives According to Biopharmaceutics Classification System (BCS), acyclovir is a class III (high solubility, low permeability) compound, and it is transported through paracellular route by passive diffusion. The aim of this study was to investigate the effect of various pharmaceutical excipients on the intestinal permeability of acyclovir.
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