Published January 1, 2016
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Effects of GnRHa on early embryonic development in mice receiving cyclophosphamide
- 1. Istanbul Medeniyet Univ, Fac Med, Dept Histol & Embryol, Istanbul, Turkey
- 2. Trakya Univ, Fac Med, Dept Histol & Embryol, TR-22030 Edirne, Turkey
- 3. Sarikamis State Hosp, Dept Thorac Surg, Kars, Turkey
Description
There is a controversy whether GnRH agonist can reduce the deleterious effects of chemotherapy to prevent ovarian failure. We aimed to examine the possible protective effects of a gonadotrophin-releasing hormone agonist (GnRHa) on the fertilization rate and sequential embryonic development in mouse oocytes exposed to Cy.
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