Yayınlanmış 1 Ocak 2016 | Sürüm v1
Dergi makalesi Açık

Methylsulfonyl Zn phthalocyanine: A polyvalent and powerful hydrophobic photosensitizer with a wide spectrum of photodynamic applications

  • 1. Gebze Tech Univ, Dept Chem, POB 141, TR-41400 Gebze, Kocaeli, Turkey
  • 2. Paracelsus Med Univ, Inst Physiol & Pathophysiol, Lab Tumour Biol & Expt Therapies, Strubergasse 21, A-5020 Salzburg, Austria
  • 3. Salzburg Univ, Dept Mat Sci & Phys, Lab Photodynam Inactivat Microorganisms, Hellbrunnerstr 34, A-5020 Salzburg, Austria

Açıklama

Background: The biomedical photodynamic principle is based on the light-induced and photosensitizer-mediated killing of unwanted or harmful cells by overproduction of reactive oxygen species. Motivated by the success of photodynamic therapy (PDT) against several types of tumors, further applications of this approach are constantly identified which require the design and synthesis of novel photosensitizers with specifically tailored properties for a particular clinical application.

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