Published January 1, 2016 | Version v1
Journal article Open

Identification of miR-139-5p as a saliva biomarker for tongue squamous cell carcinoma: a pilot study

  • 1. Istanbul Univ, Cerrahpasa Med Sch, Dept Med Genet, Istanbul, Turkey
  • 2. Erzurum Tech Univ, Dept Mol Biol & Genet, Erzurum, Turkey
  • 3. Istanbul Univ, Cerrahpasa Med Sch, Dept Otorhinolaryngol, Istanbul, Turkey

Description

Of all human oral carcinomas, 41 % are localized to the tongue. Despite considerable improvements in both diagnosis and treatment, tongue squamous cell carcinoma (TSCC) has remained one of the most lethal types of cancer. Here, we aimed at identifying a salivary microRNA (miRNA) expression signature specific for TSCC patients.

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